Picot Laurent
- Équipe de rattachement : BCBS
- Statut : Chercheur
- laurent.picot*at*univ-lr.fr
- Tél. : +33 (O)5 46 45 82 20
Enseignant-chercheur, Maître de Conférences
Université de La Rochelle
Section de Recherche : CNU 64
Institut scientifique du CNRS référent : INEE
Mots clés : Anticancéreux, microalgues marines, pigments, hétérocycles, pharmacologie
- Animateur des thématiques de recherche "Pigments marins et Photothérapie dynamique des tumeurs" et "Composition et activité pharmacologique de plantes terrestres Brésiliennes"
- Responsable pour l’université de La Rochelle du Projet Européen Interreg Enhance Microalgae
- Editeur invité numéro spécial "Antiproliferative Marine Natural products" de la revue "Marine Drugs"
Thèmes de Recherche.
- Recherche d’anticancéreux dans l’environnement marin, pharmacologie des anticancéreux
- Extraction, purification, caractérisation moléculaire, activité pharmacologique de pigments de microalgues marines et de plantes terrestres
- Valorisation biotechnologique des ressources marines et botaniques en cancérologie
- Anticancéreux hétérocycliques
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Liste des publications :
98 résultats
2025
Article dans une revue
Polymethoxyflavones from Gardenia oudiepe and semi-synthetic derivatives reduce nociception in mice: Evidence for the involvement of the MAPK pathway
Clément Daviaud
,
Christiane Adrielly Alves Ferraz
,
Mariana Gama E Silva
,
Edilson Beserra de Alencar Filho
,
Sammya Yasmin Evangelista Mendes de Lima
,
Vincent Dumontet
,
Lucindo José Quintans Júnior
,
Jackson Roberto Guedes da Silva Almeida
,
Laurent Picot
,
Kévin Baranger
,
Raimundo Gonçalves de Oliveira Júnior
,
Raphaël Grougnet
Biomedicine and Pharmacotherapy, 2025, 182, pp.117742. ⟨10.1016/j.biopha.2024.117742⟩
2024
Article dans une revue
Exploring the therapeutic potential and chemical properties of trans-chalcone: a comprehensive review
Anamaria Mendonça Santos
,
José Adão Carvalho Nascimento Júnior
,
Silvia Vitoria Silva Cezar
,
Cláudio Carvalho Santana Júnior
,
Ana Maria Santos Oliveira
,
Laurent Picot
,
Paula Dos Passos Menezes
,
Mairim Russo Serafini
Future Medicinal Chemistry, 2024, pp.1-16. ⟨10.1080/17568919.2024.2424148⟩
Exploring the Therapeutic Potential of Theobroma cacao L.: Insights from In Vitro, In Vivo, and Nanoparticle Studies on Anti-Inflammatory and Anticancer Effects
Przemysław Sitarek
,
Anna Merecz-Sadowska
,
Joanna Sikora
,
Weronika Osicka
,
Igor Śpiewak
,
Laurent Picot
,
Tomasz Kowalczyk
Antioxidants , 2024, 13 (11), pp.1376. ⟨10.3390/antiox13111376⟩
Flavonoids and their derivatives as DNA topoisomerase inhibitors with anti-cancer activity in various cell models: Exploring a novel mode of action
Przemysław Sitarek
,
Anna Merecz-Sadowska
,
Joanna Sikora
,
Malwina Dudzic
,
Natasza Wiertek-Płoszaj
,
Laurent Picot
,
Tomasz Śliwiński
,
Tomasz Kowalczyk
Pharmacological Research, 2024, 209 (9), pp.107457. ⟨10.1016/j.phrs.2024.107457⟩
Phototoxicity of the Ethanolic Extract of Skeletonema marinoi for the Dermocosmetic Improvement of Acne
Jean-Baptiste Bérard
,
Tan-Sothea Ouk
,
Vincent Sol
,
Louise Lefoulon
,
Cornelia Landolt
,
Karine Grenier
,
Naima Saad
,
Elise Robert
,
Manoëlla Sibat
,
Nathalie Schreiber
,
Samuel Guenin
,
Laurent Picot
Marine drugs, 2024, 22 (8), pp.343. ⟨10.3390/md22080343⟩
Deprotonative Metallation of Benzofuran and Benzothiophene Derivatives for the Formation of Tetracyclic and Pentacyclic Heteroaromatic Compounds
Loubna Elmir
,
Ghenia Bentabed-Ababsa
,
William Erb
,
Thierry Roisnel
,
Jean-Pierre Hurvois
,
Laurent Picot
,
Valérie Thiéry
,
Florence Mongin
European Journal of Organic Chemistry, 2024, 27 (27), ⟨10.1002/ejoc.202400374⟩
The Identification of Peptide Inhibitors of the Coronavirus 3CL Protease from a Fucus ceranoides L. Hydroalcoholic Extract Using a Ligand-Fishing Strategy
Luiz Antonio Miranda de Souza Duarte Filho
,
Cintia Emi Yanaguibashi Leal
,
Pierre-Edouard Bodet
,
Edilson Beserra de Alencar Filho
,
Jackson Roberto Guedes da Silva Almeida
,
Manon Porta Zapata
,
Oussama Achour
,
Hugo Groult
,
Carlos Arthur Gouveia Veloso
,
Claudio Viegas Júnior
,
Nathalie Bourgougnon
,
Laurent Picot
Marine drugs, 2024, 22 (6), pp.244. ⟨10.3390/md22060244⟩
The protective effects of naringenin, a citrus flavonoid, non-complexed or complexed with hydroxypropyl-β-cyclodextrin against multiorgan damage caused by neonatal endotoxemia
Luana Heimfarth
,
Katielen Silvana dos Santos
,
Brenda Souza Monteiro
,
Anne Karoline de Souza Oliveira
,
Henrique Douglas M. Coutinho
,
Irwin R.A. Menezes
,
Marcio Roberto Viana dos Santos
,
Adriano Antunes de Souza Araújo
,
Laurent Picot
,
Raimundo Gonçalves de Oliveira Júnior
,
Raphaël Grougnet
,
Jullyana de Souza Siqueira Quintans
,
Lucindo José Quintans-Júnior
International Journal of Biological Macromolecules, 2024, 264, pp.130500. ⟨10.1016/j.ijbiomac.2024.130500⟩
The Precious Potential of the Sacred Tree Chamaecyparis obtusa (Siebold & Zucc.) Endl. as a Source of Secondary Metabolites with Broad Biological Applications
Karol Maksymilian Górski
,
Tomasz Kowalczyk
,
Laurent Picot
,
Patricia Rijo
,
Mansour Ghorbanpour
,
Przemysław Sitarek
International Journal of Molecular Sciences, 2024, 25 (5), pp.2723. ⟨10.3390/ijms25052723⟩
The antiproliferative activity of Varronia dardani (Taroda) J.S. Mill. roots against human melanoma cells and the isolation of a new hydroanthraquinone
Carlos Arthur Gouveia Veloso
,
César Augusto Gonçalves Dantas
,
Raimundo Gonçalves de Oliveira Júnior
,
Vicente Carlos de Oliveira Costa
,
Luiz Antonio Miranda de Souza Duarte-Filho
,
José Iranildo Miranda de Melo
,
Pierre Edouard Bodet
,
Josean Fechine Tavares
,
Marcelo Sobral da Silva
,
Laurent Picot
Phytochemistry Letters, 2024, 59, pp.45-52. ⟨10.1016/j.phytol.2023.12.004⟩
In vitro antiherpetic activity of compounds extracted from Sargassum fluitans (Børgesen) Børgesen. Identification and in silico evaluation of potential antiviral molecules in a hydroalcoholic extract
Liena de Regla Ponce Rey
,
Hugo Pliego-Cortés
,
Christel Marty
,
Enrique Colina Araujo
,
Sonia Resik
,
Idania Rodeiro Guerra
,
Pierre Edouard Bodet
,
Laurent Picot
,
Nathalie Bourgougnon
Journal of Applied Phycology, 2024, ⟨10.1007/s10811-024-03202-4⟩
Anti-Inflammatory and Anticancer Effects of Anthocyanins in In Vitro and In Vivo Studies
Tomasz Kowalczyk
,
Martyna Muskała
,
Anna Merecz-Sadowska
,
Joanna Sikora
,
Laurent Picot
,
Przemysław Sitarek
Antioxidants , 2024, Natural Products: Biological, Antioxidant Properties and Health Effects—3rd Edition), 13 (9), pp.1143. ⟨10.3390/antiox13091143⟩
2023
Article dans une revue
Anti-melanoma potential of inclusion complexes containing phyllacanthone in β-cyclodextrin and sulfobutyl-ether-β-cyclodextrin
Cristiane dos Santos Cerqueira Alves
,
Yuri Kelvin Silva Camacho Tavares
,
Guilherme Urias Menezes Novaes
,
Victória Laysna dos Anjos Santos
,
Ana Paula de Oliveira
,
Cintia Emi Yanaguibashi Leal
,
Edilson Beserra de Alencar Filho
,
Christiane Adrielly Alves Ferraz
,
Laurent Picot
,
Jackson Roberto Guedes da Silva Almeida
,
Raimundo Gonçalves de Oliveira Júnior
Journal of Drug Delivery Science and Technology, 2023, 89, pp.105020. ⟨10.1016/j.jddst.2023.105020⟩
The decapod crustacean fauna from the Late Jurassic of Cricqueboeuf, Normandy (France)
Sylvain Charbonnier
,
Alessandro Garassino
,
Damien Gendry
,
Julien Devillez
,
Laurent Picot
Geodiversitas, 2023, 45 (19), ⟨10.5252/geodiversitas2023v45a19⟩
From benzofuro-, benzothieno- and 10-methylindolo-[2,3-b]-fused benzothiopyrano[4,3,2-de]quinolines to the corresponding benzothiopyrano[4,3,2-de]1,8-naphthyridines: synthesis and properties of these hexacyclic heteroaromatic compounds
Nicolas Mast
,
William Erb
,
Lionel Nauton
,
Pascale Moreau
,
Olivier Mongin
,
Thierry Roisnel
,
Margaux Macaigne
,
Thomas Robert
,
Stéphane Bach
,
Laurent Picot
,
Valérie Thiéry
,
Jean-Pierre Hurvois
,
Florence Mongin
New Journal of Chemistry, 2023, 47 (1), pp.258-283. ⟨10.1039/D2NJ04567B⟩
Biological effect of natural chitosan nanoparticles with transformed roots extract of Leonotis nepetifolia (L.) R.Br. in an in vitro model
Tomasz Kowalczyk
,
Monika Owczarek
,
Ewelina Synowiec
,
Tomasz Śliwiński
,
Anna Merecz-Sadowska
,
Laurent Picot
,
Przemysław Sitarek
Industrial Crops and Products, 2023, 203, pp.117135. ⟨10.1016/j.indcrop.2023.117135⟩
Ligand fishing as a tool to screen natural products with anticancer potential
Luiz Antonio Miranda de Souza Duarte-Filho
,
Pamella Christina Ortega de Oliveira
,
Cíntia Emi Yanaguibashi Leal
,
Marcela Cristina de Moraes
,
Laurent Picot
Journal of Separation Science, 2023, 46 (12), pp.2200964. ⟨10.1002/jssc.202200964⟩
A review of phototoxic plants, their phototoxic metabolites, and possible developments as photosensitizers.
Raphaelle Petit
,
Jonathan Izambart
,
Mathieu Guillou
,
Jackson Guedes da Silva Almeida
,
Raimundo Gonçalves de Oliveira Junior
,
Vincent Sol
,
Tan-Sothea Ouk
,
Raphael Grougnet
,
Lucindo Quintans-Junior
,
Przemyslaw Sitarek
,
Valérie Thiéry
,
Laurent Picot
Chemistry and Biodiversity, 2023, ⟨10.1002/cbdv.202300494⟩
Communication dans un congrès
Les crustacés de l'Oxfordien supérieur de Cricqueboeuf (Normandie, France)
Sylvain Charbonnier
,
Alessandro Garassino
,
Damien Gendry
,
Julien Devillez
,
Laurent Picot
28e Réunion des Sciences de la Terre, Université de Rennes; Société Géologique de France, Oct 2023, Rennes, France
2022
Article dans une revue
Bisphosphonylallenes as Suitable Scaffolds for Unprecedented 4,5-Diphosphonyldihydropyridazines and 3,4-Diphosphonylpyrroles Displaying Antimelanoma Activity
Kmar Abaid
,
William Erb
,
David Virieux
,
Laurent Picot
,
Benjamin Musnier
,
Valérie Thiéry
,
Thierry Roisnel
,
Florence Mongin
,
Soufiane Touil
ACS Omega, 2022, 7 (43), pp.38894-38901. ⟨10.1021/acsomega.2c04619⟩
Anticancer Properties of Plectranthus ornatus-Derived Phytochemicals Inducing Apoptosis via Mitochondrial Pathway
Przemysław Sitarek
,
Ewelina Synowiec
,
Tomasz Kowalczyk
,
Gabrielle Bangay
,
Tomasz Śliwiński
,
Laurent Picot
,
Salvatore Princiotto
,
Patricia Rijo
International Journal of Molecular Sciences, 2022, 23 (19), pp.11653. ⟨10.3390/ijms231911653⟩
Carotenoids from Marine Microalgae as Antimelanoma Agents
Christiane Adrielly Alves Ferraz
,
Raphaël Grougnet
,
Elodie Nicolau
,
Laurent Picot
,
Raimundo Gonçalves de Oliveira Junior
Marine drugs, 2022, 20 (10), pp.618. ⟨10.3390/md20100618⟩
Archaea Carotenoids: Natural Pigments with Unexplored Innovative Potential
Antoine Grivard
,
Isabelle Goubet
,
Luiz Miranda de Souza Duarte Filho
,
Valérie Thiéry
,
Sylvie Chevalier
,
Raimundo Gonçalves de Oliveira Júnior
,
Noureddine El Aouad
,
Jackson Roberto Guedes da Silva Almeida
,
Przemysław Sitarek
,
Lucindo José Quintans-Junior
,
Raphaël Grougnet
,
Hélène Agogué
,
Laurent Picot
Marine drugs, 2022, Marine Pigments, 20 (8), pp.524. ⟨10.3390/md20080524⟩
First description of the most complete Metriorhynchus aff. superciliosus (Thalattosuchia) specimen from the Callovian of the Vaches-Noires cliffs (Normandy, France) and limitations in the classification of Metriorhynchidae
Jonas Le Mort
,
Jeremy Martin
,
Laurent Picot
,
Stéphane Hua
Annales de Paléontologie, 2022, 108 (3), pp.102539. ⟨10.1016/j.annpal.2022.102539⟩
Fucoxanthin from Algae to Human, an Extraordinary BioreSource: Insights and Advances in up and Downstream Processes
Anne Pajot
,
Gia Hao Huynh
,
Laurent Picot
,
Luc Marchal
,
Elodie Nicolau
Marine drugs, 2022, 20 (4), pp.222. ⟨10.3390/md20040222⟩
New data on the theropod diversity from the Middle to Late Jurassic of the Vaches Noires cliffs (Normandy, France)
Evariste Monvoisin
,
Ronan Allain
,
Eric Buffetaut
,
Laurent Picot
Geodiversitas, 2022, 44 (12), ⟨10.5252/geodiversi-tas2022v44a12⟩
Bis-nor-diterpene from Cnidoscolus quercifolius (Euphorbiaceae) induces tubulin depolymerization-mediated apoptosis in BRAFmutated melanoma cells
Raimundo Gonçalves de Oliveira-Júnior
,
Christiane Adrielly Alves Ferraz
,
Ana Paula de Oliveira
,
Edigênia Cavalcante da Cruz Araújo
,
Grégoire Prunier
,
Laureen Beaugeard
,
Hugo Groult
,
Laurent Picot
,
Edilson Beserra de Alencar Filho
,
Noureddine El Aouad
,
Larissa Araújo Rolim
,
Jackson Roberto Guedes da Silva Almeida
Chemico-Biological Interactions, 2022, 355, pp.109849. ⟨10.1016/j.cbi.2022.109849⟩
Genetic Manipulation and Bioreactor Culture of Plants as a Tool for Industry and Its Applications
Tomasz Kowalczyk
,
Anna Merecz-Sadowska
,
Laurent Picot
,
Irena Brčić Karačonji
,
Joanna Wieczfinska
,
Tomasz Śliwiński
,
Przemysław Sitarek
Molecules, 2022, 27 (3), pp.795. ⟨10.3390/molecules27030795⟩
The Franco-Brazilian network on natural products (FB2NP): a new network promoting cooperation and exchanges in natural products research
Jackson Almeida
,
Raphaël Grougnet
,
Lucindo Quintans
,
Sylvie Chevalier
,
Marc Feuilloley
,
Thomas Robert
,
Stéphane Bach
,
Raimundo Oliveira
,
Valérie Thiéry
,
Jean-Pierre Bazureau
,
Florence Mongin
,
Marina Kritsanida
,
Vincent Sol
,
Vicente Costa
,
Nathalie Bourgougnon
,
Pascal Marchand
,
Laurent Picot
Química Nova, 2022, 45, pp.1-3. ⟨10.21577/0100-4042.20170847⟩
2021
Article dans une revue
Thiazolo[5,4- f ]quinoxalines, Oxazolo[5,4- f ]quinoxalines and Pyrazino[ b,e ]isatins: Synthesis from 6-Aminoquinoxalines and Properties
Frédéric Lassagne
,
Joshua M. Sims
,
William Erb
,
Olivier Mongin
,
Nicolas Richy
,
Nour El Osmani
,
Ziad Fajloun
,
Laurent Picot
,
Valérie Thiéry
,
Thomas Robert
,
Stéphane Bach
,
Vincent Dorcet
,
Thierry Roisnel
,
Florence Mongin
European Journal of Organic Chemistry, 2021, 2021 (19), pp.2756-2763. ⟨10.1002/ejoc.202100362⟩
Anticancer activity of limonene: A systematic review of target signaling pathways
Heitor Gomes De Araújo‐filho
,
Jucilene Santos
,
Mikaella Carvalho
,
Laurent Picot
,
Ingrid Fruitier-Arnaudin
,
Hugo Groult
,
Lucindo Quintans‐júnior
,
Jullyana S.S. Quintans
Phytotherapy Research, 2021, ⟨10.1002/ptr.7125⟩
Role of peripheral and central sensitization in the anti-hyperalgesic effect of hecogenin acetate, an acetylated sapogenin, complexed with β-cyclodextrin: Involvement of NFκB and p38 MAPK pathways
Fabiolla Rocha Santos Passos
,
Erik W.M. Pereira
,
Luana Heimfarth
,
Brenda Monteiro
,
Yasmim Maria Barbosa Gomes de Carvalho
,
Pollyana Siqueira-Lima
,
Henrique Douglas Melo Coutinho
,
Adriano Antunes de Souza Araújo
,
Jackson Roberto Guedes da Silva Almeida
,
Rosana S.S. Barreto
,
Laurent Picot
,
Lucindo Quintans-Júnior
,
Jullyana S.S. Quintans
Neuropharmacology, 2021, 186, pp.108395. ⟨10.1016/j.neuropharm.2020.108395⟩
Chemical composition and biological potential of a chloroform fraction from the leaves of marine plant Syringodium filiforme Kützing
Kethia Gonzalez
,
David Marrero
,
Yasnay Hernández
,
Yulexi Acosta Suarez
,
Richard Gutiérrez Cuesta
,
Mario Riera-Romo
,
Olga Echemendia
,
Lívia Macedo Dutra
,
Jackson Roberto Guedes da Silva Almeida
,
Dayana Pérez-Martínez
,
Laurent Picot
,
Idania Rodeiro Guerra
Pharmacognosy Magazine, 2021, 16 (72), pp.750-756. ⟨10.4103/pm.pm_24_20⟩
Iodothiophenes and Related Compounds as Coupling Partners in Copper-Mediated N-Arylation of Anilines
Salima Bouarfa
,
Ghenia Bentabed-Ababsa
,
William Erb
,
Laurent Picot
,
Valérie Thiéry
,
Thierry Roisnel
,
Vincent Dorcet
,
Florence Mongin
Synthesis: Journal of Synthetic Organic Chemistry, 2021, 53 (07), pp.1271-1284. ⟨10.1055/s-0040-1706542⟩
Preliminary Phytochemical Analysis and Evaluation of the Biological Activity of Leonotis nepetifolia (L.) R. Br Transformed Roots Extracts Obtained through Rhizobium rhizogenes-Mediated Transformation
Tomasz Kowalczyk
,
Anna Merecz-Sadowska
,
Patricia Rijo
,
Vera M S Isca
,
Laurent Picot
,
Marzena Wielanek
,
Tomasz Śliwiński
,
Przemysław Sitarek
Cells, 2021, 10 (5), pp.1242. ⟨10.3390/cells10051242⟩
Improving Microalgae Research and Marketing in the European Atlantic Area: Analysis of Major Gaps and Barriers Limiting Sector Development
Judith Rumin
,
Raimundo Gonçalves de Oliveira Junior
,
Jean-Baptiste Bérard
,
Laurent Picot
Marine drugs, 2021, 19 (6), pp.319. ⟨10.3390/md19060319⟩
2020
Article dans une revue
Updated pigment composition of Tisochrysis lutea and purification of fucoxanthin using centrifugal partition chromatography coupled to flash chromatography for the chemosensitization of melanoma cells
Raimundo Gonçalves de Oliveira-Júnior
,
Raphaël Grougnet
,
Pierre-Edouard Bodet
,
Antoine Bonnet
,
Elodie Nicolau
,
Ahlem Jebali
,
Judith Rumin
,
Laurent Picot
Algal Research - Biomass, Biofuels and Bioproducts, 2020, 51, pp.102035. ⟨10.1016/j.algal.2020.102035⟩
Limonene, a food additive, and its active metabolite perillyl alcohol improve regeneration and attenuate neuropathic pain after peripheral nerve injury: Evidence for IL-1β, TNF-α, GAP, NGF and ERK involvement
Heitor Araújo-Filho
,
Erik W.M. Pereira
,
Luana Heimfarth
,
Brenda Souza Monteiro
,
Fabiolla Rocha Santos Passos
,
Pollyana Siqueira-Lima
,
Sathiyabama Gandhi
,
Márcio Roberto Viana dos Santos
,
Jackson Roberto Guedes da Silva Almeida
,
Laurent Picot
,
Raphaël Grougnet
,
Ray Almeida
,
Henrique Douglas Melo Coutinho
,
Lucindo Quintans-Júnior
,
Natália Martins
,
Jullyana S.S. Quintans
International Immunopharmacology, 2020, 86, pp.106766. ⟨10.1016/j.intimp.2020.106766⟩
2-Aminobenzaldehyde, a common precursor to acridines and acridones endowed with bioactivities
Sarah Zeghada
,
Ghenia Bentabed-Ababsa
,
Olivier Mongin
,
William Erb
,
Laurent Picot
,
Valérie Thiéry
,
Thierry Roisnel
,
Vincent Dorcet
,
Florence Mongin
Tetrahedron, 2020, 76 (38), pp.131435. ⟨10.1016/j.tet.2020.131435⟩
Complexation with β-cyclodextrin enhances apoptosis-mediated cytotoxic effect of harman in chemoresistant BRAF-mutated melanoma cells
Christiane Adrielly Alves Ferraz
,
Raimundo Gonçalves de Oliveira Júnior
,
Ana Paula de Oliveira
,
Hugo Groult
,
Laureen Beaugeard
,
Laurent Picot
,
Edilson Beserra de Alencar Filho
,
Jackson Roberto Guedes da Silva Almeida
,
Xirley Pereira Nunes
European Journal of Pharmaceutical Sciences, 2020, 150, pp.105353. ⟨10.1016/j.ejps.2020.105353⟩
Polymethoxyflavones from Gardenia oudiepe (Rubiaceae) induce cytoskeleton disruption-mediated apoptosis and sensitize BRAF-mutated melanoma cells to chemotherapy
Raimundo Gonçalves de Oliveira-Júnior
,
Nolwenn Marcoult-Fréville
,
Grégoire Prunier
,
Laureen Beaugeard
,
Edilson Beserra de Alencar Filho
,
Eduard David Simões Mourão
,
Sylvie Michel
,
Lucindo José Quintans-Júnior
,
Jackson Roberto Guedes da Silva Almeida
,
Raphaël Grougnet
,
Laurent Picot
Chemico-Biological Interactions, 2020, 325, pp.109109. ⟨10.1016/j.cbi.2020.109109⟩
Analysis of Scientific Research Driving Microalgae Market Opportunities in Europe
Judith Rumin
,
Elodie Nicolau
,
Raimundo Gonçalves de Oliveira Junior
,
Claudio Fuentes-Grünewald
,
Laurent Picot
Marine drugs, 2020, 18 (5), pp.264. ⟨10.3390/md18050264⟩
Phytol, a Chlorophyll Component, Produces Antihyperalgesic, Anti-inflammatory, and Antiarthritic Effects: Possible NFκB Pathway Involvement and Reduced Levels of the Proinflammatory Cytokines TNF-α and IL-6
Alexandra Carvalho
,
Luana Heimfarth
,
Erik Willyame Menezes Pereira
,
Fabrício Santana Oliveira
,
Irwin Menezes
,
Henrique Coutinho
,
Laurent Picot
,
Angelo Roberto Antoniolli
,
Jullyana Quintans
,
Lucindo Quintans-Júnior
Journal of Natural Products, 2020, 83 (4), pp.1107-1117. ⟨10.1021/acs.jnatprod.9b01116⟩
Carotenoids from Rhodomonas salina Induce Apoptosis and Sensitize A2058 Melanoma Cells to Chemotherapy
Raimundo Gonçalves de Oliveira-Júnior
,
Élodie Nicolau
,
Antoine Bonnet
,
Grégoire Prunier
,
Laureen Beaugeard
,
Nicolas Joguet
,
Valérie Thiéry
,
Laurent Picot
Revista Brasileira de Farmacognosia, 2020, 30 (2), pp.155-168. ⟨10.1007/s43450-020-00036-2⟩
An Extract of Transgenic Senna obtusifolia L. hairy roots with Overexpression of PgSS1 Gene in Combination with Chemotherapeutic Agent Induces Apoptosis in the Leukemia Cell Line
Tomasz Kowalczyk
,
Przemysław Sitarek
,
Monika Toma
,
Laurent Picot
,
Marzena Wielanek
,
Ewa Skała
,
Tomasz Śliwiński
Biomolecules, 2020, 10 (4), pp.510. ⟨10.3390/biom10040510⟩
A Bibliometric Analysis of Microalgae Research in the World, Europe, and the European Atlantic Area
Judith Rumin
,
Elodie Nicolau
,
Raimundo Gonçalves de Oliveira Junior
,
Claudio Fuentes-Grünewald
,
Kevin J. Flynn
,
Laurent Picot
Marine drugs, 2020, 18 (2), pp.79. ⟨10.3390/md18020079⟩
Functionalization of 9-thioxanthone at the 1-position: From arylamino derivatives to [1]benzo(thio)pyrano[4,3,2-de]benzothieno[2,3-b]quinolines of biological interest
Nahida Mokhtari Brikci-Nigassa
,
Lionel Nauton
,
Pascale Moreau
,
Olivier Mongin
,
Raphael E Duval
,
Laurent Picot
,
Valérie Thiery
,
Mohamed Souab
,
Blandine Baratte
,
Sandrine Ruchaud
,
Stéphane Bach
,
Rémy Le Guével
,
Ghenia Bentabed-Ababsa
,
William Erb
,
Thierry Roisnel
,
Vincent Dorcet
,
Florence Mongin
Bioorganic Chemistry, 2020, 94, pp.103347. ⟨10.1016/j.bioorg.2019.103347⟩
Thermophysiologies of Jurassic marine crocodylomorphs inferred from the oxygen isotope composition of their tooth apatite
Nicolas Séon
,
Romain Amiot
,
Jérémy Martin
,
Mark Young
,
Heather Middleton
,
François Fourel
,
Laurent Picot
,
Xavier Valentin
,
Christophe Lécuyer
Philosophical Transactions of the Royal Society B: Biological Sciences, 2020, 375 (1793), pp.20190139. ⟨10.1098/rstb.2019.0139⟩
2019
Article dans une revue
Pre-clinical investigations of β-carboline alkaloids as antidepressant agents: A systematic review
Christiane Adrielly Alves Ferraz
,
Raimundo Gonçalves de Oliveira Júnior
,
Laurent Picot
,
Jackson Roberto Guedes da Silva Almeida
,
Xirley Pereira Nunes
Fitoterapia, 2019, 137, pp.104196. ⟨10.1016/j.fitote.2019.104196⟩
From ecological relevance of the ecosystem services concept to its socio-political use. The case study of intertidal bare mudflats in the Marennes-Oléron Bay, France
Benoit Lebreton
,
Audrey Rivaud
,
Laurent Picot
,
Benoît Prévost
,
Laurent Barillé
,
Thierry Sauzeau
,
Jennifer Beseres Pollack
,
Johann Lavaud
Ocean and Coastal Management, 2019, 172, pp.41-54. ⟨10.1016/j.ocecoaman.2019.01.024⟩
Terpenes as possible drugs for the mitigation of arthritic symptoms - a systematic review.
Alexandra M.S. Carvalho
,
Luana Heimfarth
,
Klécia Anjos
,
Adriana Gibara
,
Laurent Picot
,
Jackson Roberto Guedes da Silva Almeida
,
Jullyana de Souza Siqueira Quintans
,
Lucindo José Quintans Junior
Phytomedicine, 2019, 57, pp.137-147. ⟨10.1016/j.phymed.2018.10.028⟩
An efficient plant regeneration from Rhaponticum carthamoides transformed roots, enhanced caffeoylquinic acid derivatives production in pRi-transformed plants and their biological activity
Ewa Skała
,
Laurent Picot
,
Michał Bijak
,
Joanna Bijak
,
Janusz Szemraj
,
Agnieszka Kicel
,
Monika Olszewska
,
Przemysław Sitarek
Industrial Crops and Products, 2019, 129, pp.327-338. ⟨10.1016/j.indcrop.2018.12.020⟩
Bixin, an apocarotenoid isolated from Bixa orellana L., sensitizes human melanoma cells to dacarbazine-induced apoptosis through ROS-mediated cytotoxicity
Raimundo Gonçalves de Oliveira Júnior
,
Antoine Bonnet
,
Estelle Braconnier
,
Hugo Groult
,
Grégoire Prunier
,
Laureen Beaugeard
,
Raphäel Grougnet
,
Jackson Roberto Guedes da Silva Almeida
,
Christiane Adrielly Alves Ferraz
,
Laurent Picot
Food and Chemical Toxicology, 2019, 125, pp.549-561. ⟨10.1016/j.fct.2019.02.013⟩
Chemical constituents of non-polar fractions obtained from Cnidoscolus quercifolius Pohl (Euphorbiaceae), a Brazilian medicinal plant native to Caatinga biome Chemical constituents of non-polar fractions obtained from Cnidoscolus quercifolius Pohl (Euphorbiaceae), a Brazilian medicinal plant native to Caatinga biome
Raimundo G. de Oliveira-Júnior
,
Christiane Adrielly A. Ferraz
,
Ana Paula de Oliveira
,
José Marcos T. de Alencar-Filho
,
Edigênia C. C. Araújo
,
Xirley P. Nunes
,
Laurent Picot
,
Norberto P Lopes
,
Raimundo Braz-Filho
,
Larissa A. Rolim
,
Jackson Roberto G. da S. Almeida
Revista Virtual de Química, 2019, 11 (2), pp.498-516. ⟨10.21577/1984-6835.20190038⟩
Crystal Structure of 6,7-Dihydro-5a,7a,13,14-tetraaza-pentaphene-5,8-dione
Jean Guillon
,
Maria de Fatima Pereira-Rosenfeld
,
Noël Pinaud
,
Thierry Besson
,
Valérie Thiéry
,
Laurent Picot
,
Mathieu Marchivie
X-Ray Structure Analysis Online, 2019, 35 (10), pp.57-59. ⟨10.2116/xraystruct.35.57⟩
Monoterpenes modulating cytokines - A review
Jullyana S.S. Quintans
,
Saravanan Shanmugam
,
Luana Heimfarth
,
Adriano Antunes S. Araújo
,
Jackson R.G.da S. Almeida
,
Laurent Picot
,
Lucindo J Quintans-Júnior
Food and Chemical Toxicology, 2019, 123, pp.233-257. ⟨10.1016/j.fct.2018.10.058⟩
Citronellol, a monoterpene alcohol with promising pharmacological activities - A systematic review
Priscila Santos
,
João Pedro S.C.F. Matos
,
Laurent Picot
,
Jackson R.G.S. Almeida
,
Jullyana S.S. Quintans
,
Lucindo J. Quintans-Junior
Food and Chemical Toxicology, 2019, 123, pp.459-469. ⟨10.1016/j.fct.2018.11.030⟩
2018
Article dans une revue
Antibacterial activity of terpenoids isolated from Cnidoscolus quercifolius Pohl (Euphorbiaceae), a Brazilian medicinal plant from Caatinga biome
Raimundo Gonçalves de Oliveira-Júnior
,
Christiane Adrielly Alvez Ferraz
,
Michelle Cruz Pontes
,
Noelly Bastos Cavalcante
,
Edigênia Cavalcante da Cruz Araújoa
,
Ana Paula de Oliveira
,
Laurent Picot
,
Larissa Araújo Rolim
,
Jackson Roberto Guedes da Silva Almeida
European Journal of Integrative Medicine, 2018, 24, pp.30-34. ⟨10.1016/j.eujim.2018.10.011⟩
From Quinoxaline, Pyrido[2,3-b]pyrazine and Pyrido[3,4-b]pyrazine to Pyrazino-Fused Carbazoles and Carbolines
Frédéric Lassagne
,
Timothy Langlais
,
Elsa Caytan
,
Emmanuelle Limanton
,
Ludovic Paquin
,
Manon Boullard
,
Coline Courtel
,
Idriss Curbet
,
Clément Gédéon
,
Julien Lebreton
,
Laurent Picot
,
Valérie Thiéry
,
Mohamed Souab
,
Blandine Baratte
,
Sandrine Ruchaud
,
Stéphane Bach
,
Thierry Roisnel
,
Florence Mongin
Molecules, 2018, 23 (11), pp.2961. ⟨10.3390/molecules23112961⟩
Growth of Leonurus sibiricus L. roots with over-expression of AtPAP1 transcriptional factor in closed bioreactor, production of bioactive phenolic compounds and evaluation of their biological activity
Przemysław Sitarek
,
Tomasz Kowalczyk
,
Laurent Picot
,
Dorota Michalska-Hejduk
,
Michał Bijak
,
Adam J Białas
,
Marzena Wielanek
,
Tomasz Śliwiński
,
Ewa Skała
Industrial Crops and Products, 2018, 122, pp.732 - 739. ⟨10.1016/j.indcrop.2018.06.059⟩
Sensitization of tumor cells to chemotherapy by natural products: a systematic review of preclinical data and molecular mechanisms
Raimundo Gonçalves de Oliveira Júnior
,
Christiane Adrielly Alves Ferraz
,
Jackson Roberto Guedes da Silva Almeida
,
Raphäel Grougnet
,
Valérie Thiéry
,
Laurent Picot
Fitoterapia, 2018, 129, pp.383-400. ⟨10.1016/j.fitote.2018.02.025⟩
EnhanceMicroalgae: An European Interregional Project Stimulating Research, Innovation, Industrial Development and Transnational Cooperation within the Atlantic Area Microalgae Sector
Judith Rumin
,
Joana Martins
,
Jose Cruz
,
Vitor Vasconcelos
,
Claudio Fuentes Grünewald
,
Kevin J. Flynn
,
Alejandra Sabin
,
Maria Paredes
,
Enma Conde
,
Jose Vilarino
,
Martina Ferreira
,
Federica Farabegoli
,
Paula Fajardo
,
Maria-José Chapela
,
Laurent Picot
Journal of Oceanography and Marine Research, 2018, 6 (3), pp.1000182. ⟨10.4172/2572-3103.1000182⟩
2-Aminophenones, a common precursor to N-aryl isatins and acridines endowed with bioactivities
Nahida Mokhtari Brikci-Nigassa
,
Ghenia Bentabed-Ababsa
,
William Erb
,
Floris Chevallier
,
Laurent Picot
,
Lucille Vitek
,
Audrey Fleury
,
Valérie Thiéry
,
Mohamed Souab
,
Thomas Robert
,
Sandrine Ruchaud
,
Stéphane Bach
,
Thierry Roisnel
,
Florence Mongin
Tetrahedron, 2018, 74 (15), pp.1785-1801. ⟨10.1016/j.tet.2018.02.038⟩
Zeaxanthin from Porphyridium purpureum induces apoptosis in human melanoma cells expressing the oncogenic BRAF V600E mutation and sensitizes them to the BRAF inhibitor vemurafenib
Camille Juin
,
Raimundo Gonçalves de Oliveira Junior
,
Audrey Fleury
,
Chloé Oudinet
,
Lior Pytowski
,
Jean-Baptiste Bérard
,
Elodie Nicolau
,
Valérie Thiéry
,
Isabelle Lanneluc
,
Laureen Beaugeard
,
Grégoire Prunier
,
Jackson Roberto Guedes da Silva Almeida
,
Laurent Picot
Revista Brasileira de Farmacognosia, 2018, 28 (4), pp.457-467. ⟨10.1016/j.bjp.2018.05.009⟩
Communication dans un congrès
Natural compounds targeting pyocyanin and quorum sensing in Pseudomonas aeruginosa
Ali Tahrioui
,
Onyedikachi Cecil Azuama
,
Sergio Ortiz
,
Raimundo Gonçalves
,
Damien Tortuel
,
Olivier Maillot
,
Chouaha Bouzidi
,
Laurent Picot
,
Raphaël Grougnet
,
Sabrina Boutefnouchet
,
Marina Kritsanida
,
Marc Feuilloley
,
Nicole Orange
,
Sylvie Michel
,
Olivier Lesouhaitier
,
Emeline Bouffartigues
,
Sylvie Chevalier
Congrès National de la Société Française de Microbiologie-SFM2018, Oct 2018, Paris, France
Potential of Optical Frequency Domain Reflectometry fiber-based sensors for distributed temperature measurements during vacuum thermal cycling of satellites
Camille Sabatier
,
Adriana Morana
,
Sylvain Girard
,
Aziz Boukenter
,
Y. Ouerdane
,
Emmanuel Marin
,
Thierry Robin
,
Benoît Cadier
,
Olivier Gilard
,
Laurent Picot
European Workshop on Structural Health Monitoring Series (EWSHM 2018), Jul 2018, Manchester, United Kingdom. pp.0307
2017
Article dans une revue
Phytochemical and pharmacological aspects of Cnidoscolus Pohl species: a systematic review
Raimundo Gonçalves Oliveira
,
Christiane Adrielly Alves Ferraz
,
Ana Paula Oliveira
,
Camila Souza Araújo
,
Layanne Feitosa da Silva Oliveira
,
Laurent Picot
,
Larissa Araújo Rolim
,
Pedro José Rolim-Neto
,
Jackson Roberto Guedes da Silva Almeida
Phytomedicine, 2017, ⟨10.1016/j.phymed.2017.08.017⟩
Community analysis of pigment patterns from 37 microalgae strains reveals new carotenoids and porphyrins characteristic of distinct strains and taxonomic groups
Benoît Serive
,
Elodie Nicolau
,
Jean-Baptiste Bérard
,
Raymond Kaas
,
Virginie Pasquet
,
Laurent Picot
,
Jean-Paul Cadoret
,
Adrianna Ianora
PLoS ONE, 2017, 12 (2), ⟨10.1371/journal.pone.0171872⟩
Antimelanoma activity of Heterocapsa triquetra pigments
Quentin Haguet
,
Antoine Bonnet
,
Jean-Baptiste Bérard
,
Joelle Goldberg
,
Nicolas Joguet
,
Audrey Fleury
,
Valérie Thiéry
,
Laurent Picot
Algal Research - Biomass, Biofuels and Bioproducts, 2017, 25, pp.207 - 215. ⟨10.1016/j.algal.2017.04.034⟩
Chapitre d'ouvrage
Chapter 8 : Flavonoids: Promising Natural Products for Treatment of Skin Cancer (Melanoma). in Natural Products and Cancer Drug Discovery Edited by Farid A. Badria, ISBN
Raimundo Gonçalves de Oliveira Junior
,
Christiane Adrielly Alves Ferraz
,
Mariana Gama E Silva
,
Erica Martins de Lavor
,
Larissa Araújo Rolim
,
Julianeli Tolentino de Lima
,
Audrey Fleury
,
Laurent Picot
,
Jullyana de Souza Siqueira Quintans
,
Lucindo José Quintans Junior
,
Jackson Roberto Guedes da Silva Almeida
Natural Products and Cancer Drug Discovery , 2017
Natural products as promising pharmacological tools for the management of fibromyalgia symptoms – a review
Renan Brito Guedes
,
P. Laise Santos
,
M. Almeida Oliveira
,
Lícia Tairiny Santos Pina
,
Angelo Roberto Antoniolli
,
Jackson Roberto Guedes da Silva Almeida
,
Gokhan Zengin
,
Laurent Picot
,
Jullyana de Souza Siqueira Quintans
,
Lucindo José Quintans Junior
Fibromyalgia and Peripheral Neuropathy , 2017
2016
Article dans une revue
Could Fucoxanthin Interaction with Lipid Rafts Mediate its Cytotoxicity in Cancer Cells?
Raimundo Gonçalves Oliveira-Junior
,
Valérie Thiéry
,
Odile Sergent
,
Martine Chevanne
,
Laurent Picot
Journal of Oceanography and Marine Research, 2016, 4 (1), pp.1000144. ⟨10.4172/jomr.1000144⟩
Communication dans un congrès
Les chondrichthyens de la sériecallovo-oxfordoenne de Normandie
Marjolaine Furic
,
Jean-Philippe Pezy
,
Elisabeth Pennetier
,
Gérard Pennetier,
,
M.C. Perchey
,
Romain Vullo
,
Laurent Picot
25e Réunion des Sciences de la Terre, Société Géologique de France, Oct 2016, Caen, France. pp.134
2015
Article dans une revue
The implementation of taxonomic harmonisation for Candoninae (Ostracoda, Cypridoidea): A heuristic solution for Fabaeformiscandona tricicatricosa (Diebel and Pietrzeniuk)
D.L. Danielopol
,
Tadeusz Namiotko
,
Ulrich von Grafenstein
,
Roland Fuhrmann
,
Laurent Decrouy
,
Martin Gross
,
Maria Pichler
,
Laurent Picot
Geo-Eco-Marina, 2015, 21, pp.111-158
Azine and Diazine Functionalization Using 2,2,6,6-Tetramethylpiperidino-Based Lithium–Metal Combinations: Application to the Synthesis of 5,9-Disubstituted Pyrido[3′,2′:4,5]pyrrolo[1,2-c] pyrimidines
Nada Marquise
,
Tan Tai Nguyen
,
Floris Chevallier
,
Laurent Picot
,
Valérie Thiéry
,
Olivier Lozach
,
Stéphane Bach
,
Sandrine Ruchaud
,
Florence Mongin
SYNLETT, 2015, 26 (20), pp.2811-2816. ⟨10.1055/s-0035-1560496⟩
Deproto-metallation of N-arylated pyrroles and indoles using a mixed lithium–zinc base and regioselectivity-computed CH acidity relationship
Mohamed Yacine Ameur Messaoud
,
Ghenia Bentabed-Ababsa
,
Madani Hedidi
,
Aïcha Derdour
,
Floris Chevallier
,
Yury S. Halauko
,
Oleg A. Ivashkevich
,
Vadim E. Matulis
,
Laurent Picot
,
Valérie Thiéry
,
Thierry Roisnel
,
Vincent Dorcet
,
Florence Mongin
Beilstein Journal of Organic Chemistry, 2015, 11, pp.1475-1485. ⟨10.3762/bjoc.11.160⟩
Microwave-Assisted Extraction of Phycobiliproteins from Porphyridium purpureum.
Camille Juin
,
Jean-René Chérouvrier
,
Valérie Thiery
,
Anne-Laure Gagez
,
Jean-Baptiste Bérard
,
Nicolas, Joguet
,
Raymond Kaas
,
Jean-Paul Cadoret
,
Laurent Picot
Biotechnology and Applied Biochemistry, 2015, ⟨10.1007/s12010-014-1250-2⟩
UPLC-MSE Profiling of Phytoplankton Metabolites: Application to the Identification of Pigments and Structural Analysis of Metabolites in Porphyridium purpureum
Camille Juin
,
Antoine Bonnet
,
Elodie Nicolau
,
Jean-Baptiste Bérard
,
Devillers, Romain
,
Valérie Thiéry
,
Jean-Paul Cadoret
,
Laurent Picot
Marine drugs, 2015, 13 (4), pp.1541-2558. ⟨10.3390/md13042541⟩
2014
Article dans une revue
Synthesis of C,N'-linked bis-heterocycles using a deprotometalation-iodination-N-arylation sequence and evaluation of their antiproliferative activity in melanoma cells
Madani Hedidi
,
Ghenia Bentabed-Ababsa
,
Aicha Derdour
,
Thierry Roisnel
,
Vincent Dorcet
,
Floris Chevallier
,
Laurent Picot
,
Valérie Thiery
,
Mongin Florence
Bioorganic and Medicinal Chemistry, 2014, 22 (13), pp.3498-3507. ⟨10.1016/j.bmc.2014.04.028⟩
2013
Article dans une revue
Synthesis of azafluorenones and related compounds using deprotocupration-aroylation followed by intramolecular direct arylation
Nada Marquise
,
Philip J. Harford
,
Floris Chevallier
,
Thierry Roisnel
,
Vincent Dorcet
,
Anne-Laure Gagez
,
Sophie Sablé
,
Laurent Picot
,
Valérie Thiéry
,
Andrew E. H. Wheatley
,
Philippe C. Gros
,
Florence Mongin
Tetrahedron, 2013, 69 (47), pp.10123-10133. ⟨10.1016/j.tet.2013.09.030⟩
Antiproliferative Activity of Cyanophora paradoxa Pigments in Melanoma, Breast and Lung Cancer Cells
Paul-Hubert Baudelet
,
Anne-Laure Gagez
,
Jean-Baptiste Berard
,
Camille Juin
,
Nicolas Bridiau
,
Raymond Kaas
,
Valerie Thiery
,
Jean-Paul Cadoret
,
Laurent Picot
Marine drugs, 2013, 11 (11), pp.4390-4406. ⟨10.3390/md11114390⟩
Antiproliferative Activity of Cyanophora paradoxa Pigments in Melanoma, Breast and Lung Cancer Cells
Paul-Hubert Baudelet
,
Anne-Laure Gagez
,
Jean-Baptiste Bérard
,
Camille Juin
,
Nicolas Bridiau
,
Raymond Kaas
,
Valérie Thiéry
,
Jean-Paul Cadoret
,
Laurent Picot
Marine drugs, 2013, 11 (11), pp.4390-4406
Towards the Clinical Use of Phytoplankton Carotenoid Pigments to Cure Cancer
Camille Juin
,
Valérie Thiéry
,
Jean-Paul Cadoret
,
Laurent Picot
oceanography, open access, 2013, 1 (3), ⟨10.4172/2332-2632.1000e105⟩
Communication dans un congrès
Une approche numérique pour la simulation d´un examen de mammographie
Hervé Drobez
,
Hervé Reynaud
,
Laurent Picot
,
Haidar Jaffal
,
Virginie Corre
,
Remy Klausz
,
Serge Muller
CFM 2013 - 21ème Congrès Français de Mécanique, Aug 2013, Bordeaux, France
2012
Article dans une revue
The Potential of Microalgae for the Production of Bioactive Molecules of Pharmaceutical Interest
Virginie Mimouni
,
Lionel Ulmann
,
Virginie Pasquet
,
Marie Mathieu
,
Laurent Picot
,
Gaël Bougaran
,
Jean-Paul Cadoret
,
Annick Morant-Manceau
,
Benoît Schoefs
Current Pharmaceutical Biotechnology, 2012, 13 (15), pp.2733-2750. ⟨10.2174/138920112804724828⟩
Selection and optimisation of a method for efficient metabolites extraction from microalgae
Benoit Serive
,
Raymond Kaas
,
Jean-Baptiste Berard
,
Virginie Pasquet
,
Laurent Picot
,
Jean-Paul Cadoret
Bioresource Technology, 2012, 124, pp.311-320. ⟨10.1016/j.biortech.2012.07.105⟩
2011
Article dans une revue
Antiproliferative Activity of Violaxanthin Isolated from Bioguided Fractionation of Dunaliella tertiolecta Extracts
Virginie Pasquet
,
Perrine Morisset
,
Saïd Ihammouine
,
Amandine Chepied
,
Lucie Aumailley
,
Jean-Baptiste Bérard
,
Benoît Serive
,
Raymond Kaas
,
Isabelle Lanneluc
,
Valérie Thiéry
,
Mathieu Lafferriere
,
Jean-Marie Piot
,
Thierry Patrice
,
Jean-Paul Cadoret
,
Laurent Picot
Marine drugs, 2011, 9 (5), pp.819-831. ⟨10.3390/md9050819⟩
Study on the microalgal pigments extraction process: Performance of microwave assisted extraction
Virginie Pasquet
,
Jean-Rene Cherouvrier
,
Firas Farhat
,
Valerie Thiery
,
Jean-Marie Piot
,
Jean-Baptiste Berard
,
Raymond Kaas
,
Benoit Serive
,
Thierry Patrice
,
Jean-Paul Cadoret
,
Laurent Picot
Process Biochemistry, 2011, 46 (1), pp.59-67. ⟨10.1016/j.procbio.2010.07.009⟩
Antiproliferative Activity of Violaxanthin Isolated from Bioguided Fractionation of Dunaliella tertiolecta Extracts
Virginie Pasquet
,
Perrine Morisset
,
Saïd Ihammouine
,
Amandine Chepied
,
Lucie Aumailley
,
Jean-Baptiste Bérard
,
Benoît Serive
,
Raymond Kaas
,
Isabelle Lanneluc
,
Valérie Thiéry
,
Mathieu Lafferière
,
Jean-Marie Piot
,
Thierry Patrice
,
Jean-Paul Cadoret
,
Laurent Picot
Marine drugs, 2011, 9, pp.819-831. ⟨10.3390/md9050819⟩
2010
Article dans une revue
Impact of ultrafiltration and nanofiltration of an industrial fish protein hydrolysate on its bioactive properties
Laurent Picot
,
Rozenn Ravallec
,
Martine Fouchereau-Peron
,
Laurent Vandanjon
,
Pascal Jaouen
,
Maryse Chaplain-Derouiniot
,
Fabienne Guérard
,
Aurelie Chabeaud
,
Yves Legal
,
Oscar Martinez Alvarez
,
Jean-Pascal Bergé
,
Jean-Marie Piot
,
Irineu Batista
,
Carla Pires
,
Gudjon Thorkelsson
,
Charles Delannoy
,
Greta Jakobsen
,
Inez Johansson
,
Patrick Bourseau
Journal of the Science of Food and Agriculture, 2010, 90 (11), pp.1819-1826. ⟨10.1002/jsfa.4020⟩
2009
Article dans une revue
Synthesis and antitumoral activity of novel thiazolobenzotriazole, thiazoloindolo[3,2-c]quinoline and quinolinoquinoline derivatives
Anne Beauchard
,
Alexis Jaunet
,
Laurence Murillo
,
Brigitte Baldeyrou
,
Amélie Lansiaux
,
Jean-René Chérouvrier
,
Lisianne Domon
,
Laurent Picot
,
Christian Bailly
,
Thierry Besson
European Journal of Medicinal Chemistry, 2009, 44 (10), pp.3858-3865. ⟨10.1016/j.ejmech.2009.04.012⟩
2008
Article dans une revue
Microwave-assisted Synthesis of Novel Thiazolocarbazoles and Evaluation as Potential Anticancer Agents. Part III
Alexandra Testard
,
Laurent Picot
,
Ingrid Fruitier-Arnaudin
,
Jean-Marie Piot
,
Hadjila Chabane
,
Lisianne Domon
,
Valérie Thiery
,
Thierry Besson
Journal of Enzyme Inhibition and Medicinal Chemistry, 2008, 19 (6), pp.467-473. ⟨10.1080/14756360412331280491⟩
2007
Article dans une revue
Synthesis and antiproliferative activity of clausine E, mukonine, and koenoline bioisosteres
François Liger
,
Florence Popowycz
,
Thierry Besson
,
Laurent Picot
,
Carlos Galmarini
,
Benoît Joseph
Bioorganic and Medicinal Chemistry Letters, 2007, 15 (16), pp.5615-5619. ⟨10.1016/j.bmc.2007.05.033⟩
2005
Article dans une revue
Synthesis and evaluation of the antiproliferative activity of novel thiazoloquinazolinone kinases inhibitors.
Alexandra Testard
,
Laurent Picot
,
Olivier Lozach
,
Melina Blairvacq
,
Laurent Meijer
,
Laurence Murillo
,
Jean-Marie Piot
,
Valérie Thiéry
,
Thierry Besson
Journal of Enzyme Inhibition and Medicinal Chemistry, 2005, 20 (6), pp.557-568. ⟨10.1080/14756360500212399⟩
2004
Article dans une revue
Regulation of the cytotoxic effects of Pseudomonas fluorescens by growth temperature
Laurent Picot
,
Sana Mezghani-Abdelmoula
,
Sylvie Chevalier
,
Annabelle Merieau
,
Olivier Lesouhaitier
,
Josette Guerillon
,
Lionel Cazin
,
Nicole Orange
,
Marc G.J. Feuilloley
Research in Microbiology, 2004, 155 (1), pp.39-46. ⟨10.1016/j.resmic.2003.09.014⟩
2003
Article dans une revue
Cytotoxic effects of the lipopolysaccharide from Pseudomonas fluorescens on neurons and glial cells
Laurent Picot
,
Sylvie Chevalier
,
Sana Mezghani-Abdelmoula
,
Annabelle Mérieau
,
Olivier Lesouhaitier
,
Philippe Leroux
,
Lionel Cazin
,
Nicole Orange
,
Marc G.J Feuilloley
Microbial Pathogenesis, 2003, 35 (3), pp.95-106. ⟨10.1016/s0882-4010(03)00092-5⟩
2001
Article dans une revue
Pseudomonas fluorescens as a potential pathogen: adherence to nerve cells
Laurent Picot
,
Sana Mezghani Abdelmoula
,
Annabelle Mérieau
,
Philippe Leroux
,
Lionel Cazin
,
Nicole Orange
,
Marc G.J Feuilloley
Microbes and Infection, 2001, 3 (12), pp.985-995. ⟨10.1016/s1286-4579(01)01462-9⟩